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Novo Nordisk's Oral Semaglutide for Type 2 Diabetes Reduces Cardiovascular Risk in Late-Stage Study G-HEDE1E416Y
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By newsdecensored
October 22, 2024 10:22 am
Food & Health
36 views 2 min read

Novo Nordisk’s Oral Semaglutide for Type 2 Diabetes Reduces Cardiovascular Risk in Late-Stage Study

Novo Nordisk announced on Monday that its oral semaglutide medication, Rybelsus, reduced a central composite of cardiovascular events by 14 percent, including cardiovascular death, nonfatal myocardial infarction, and cerebrovascular accidents, according to a late-stage study. The trial comprised 9,650 patients with type 2 diabetes and either established cardiovascular disease or chronic kidney disease, and the drug was assessed along with standard care. It is one of the company’s preeminent achievements, as it continues to improve its available therapies.

The research study result met the clinical trial’s primary objective, confirming its potential as a solid treatment for patients with diabetes and cardiac conditions. More importantly, these results cement the importance of Rybelsus for patients who have type 2 diabetes, a highly vulnerable segment to cardiac conditions.

Novo Nordisk said it intends to seek a label expansion for Rybelsus in the United States and the European Union before the end of the year. It also plans to present some trial results at one of next year’s scientific conferences to illuminate its wider clinical uses.

Meanwhile, Novo Nordisk keeps pushing forward on all fronts. The CEO and President of Catalent, Alessandro Maselli, tried to give mixed reactions to some of the worries that had begun to circulate about the recent acquisition of the contract pharmaceutical manufacturer Catalent by Novo Holdings by saying Catalent would remain operationally independent. This has been very controversial as much concern arose due to fears that it may compromise competition in weight-loss and gene therapies, especially concerning one of the most widely prescribed weight-loss medications of Novo’s, Wegovy.

Maselli said the real goal of the deal is to optimize a supply chain for a critical drug like Wegovy rather than crushing competition. Consumer advocacy groups and labour unions have appealed to the US Federal Trade Commission to halt Novo’s $16.5 billion Catalent deal. He belittled those myths around the buyout. Catalent will remain independent, but contract manufacturing will be its core business.

Rybelsus’s ability to control cardiovascular risk adds to the success story of business strategy while consolidating the company at the forefront of diabetes management and weight-loss drugs. With expansion ambitions on drug pipelines and ensuring stakeholders’ satisfaction about the recently consummated acquisition, Novo Nordisk is fast-forwarding toward significant positions in the next pharmaceutical landscape.

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